A joint project of Prof. Dr. rer. nat. Harald Herrman and Prof. Dr. med. Rolf Schröder, which recently recieved funding by the Deutsche Forschungsgemeinschaft (DFG), started on February 1st, 2017.
The project entitled „Cellular mechanisms leading to desminopathy: Segregation, aggregation and proteostasis imbalance of desmin mutants in muscle cells and tissue“ aims to clarify the cellular mechanisms that are responsible for the specific sorting of wildtype versus mutant intermediate filament proteins in the context of human protein aggregate myopathies. and cardiomyopathies due to hetero- and homozygous desmin mutations.